“Tooth loss is a risk factor for cognitive impairment and dementia—and with each tooth lost, the risk of cognitive decline grows.”

“Tooth loss and incidence of periodontal disease is highly correlated to patients with Parkinson’s disease.”

“Individuals with tooth loss had a higher risk for dementia than those without tooth loss.”

“The loss of occlusal support may lead to cognitive dysfunction through the reduction of chewing-related stimuli, aggravation of nerve damage, and long-term inflammatory stress.”

“Significant relationships were found between the number of remaining teeth, the length of the edentulous period, and cognitive function. Within the limitation of no APOE genotyping data, this cross-sectional study suggests a significant relationship of tooth loss to MMI and cognitive impairment.”